New directions for chemoprevention research at the National Cancer Institute
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New directions for chemoprevention research at the National Cancer Institute report of the Chemoprevention Implementation Group, September 10, 1999. by

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Published by National Cancer Institute, Division of Cancer Prevention in [Bethesda, Md.?] .
Written in English


  • Cancer -- Chemotherapy -- United States.,
  • Cancer -- Treatment -- United States.

Book details:

Edition Notes

SeriesNIH publication -- no. 94-3701.
ContributionsNational Cancer Institute (U.S.). Division of Cancer Prevention and Control.
The Physical Object
Pagination45 p. :
Number of Pages45
ID Numbers
Open LibraryOL17702312M

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Aug 16,  · Introduction. Often, people think cancer research is about developing new treatments. But finding ways to prevent cancer is also important. More than , Canadians are expected to be diagnosed with cancer this year, and this number will keep increasing as our population grows and ages, placing a significant burden on the health care system. Oct 21,  · Cancer Chemoprevention: Progress and Promise the National Cancer Institute has restated its confidence in closing the BCPT early and in the trial's definitive positive answer to the question of whether tamoxifen prevented breast cancer in the high-risk study population. provide especially strong indications for new directions in Cited by: Part of the Recent Results in Cancer Research book series (RECENTCANCER, Division of Cancer Prevention National Cancer Institute Bethesda USA; Szabo E., Kalebic T. () Chemoprevention of Lung Cancer: New Directions. In: Senn HJ., Morant R. (eds) Tumor Prevention and Genetics. Recent Results in Cancer Research, vol Springer Cited by: 1. National Cancer Institute, Bethesda, MD. K likes. NCI is the lead federal agency for cancer research. Connect with us here, call us at CANCER, or visit us at

Up-to-date and highly practical, Cancer Chemoprevention, Volumes 1 & 2, offer oncologists, pharmacologists, medicinal chemists, and toxicologists a comprehensive reference survey on the identification of those promising cancer chemopreventive agents that will help stimulate further research and the development of novel approvable drugs. The authors also note the growing need for cancer survivorship research as the number of people who survive cancer continues to swell. Development of risk prediction models and studies of the microbiome are other areas that are highlighted in the new edition as crucial areas for future development. May 16,  · Michael B. Sporn, M.D., coined the term chemoprevention in a article in Federation Proceedings when writing about the work his group was doing with vitamin A analogues. Sporn, then of the Carcinogenesis Program at the National Cancer Institute, and others were doing the first work with agents that could be used to prevent by: The aim of cancer chemoprevention is disruption or delay of the molecular pathways that lead to carcinogenesis. Chemopreventive blocking and/or suppressing agents disrupt the molecular mechanisms that drive carcinogenesis such as DNA damage by reactive oxygen species, increased signal transduction to NF-κB, epigenomic deregulation, and the epithelial mesenchymal transition that leads Cited by:

Jul 09,  · Cancer chemoprevention involves the chronic administration of a synthetic, natural or biological agent to reduce or delay the occurrence of malignancy. The Early Detection Research Network of the National Cancer Institute (United States) Chemoprevention is a relatively new field for research. In recent years, preclinical and clinical Cited by: Full Text CA RESEARCH PROGRAM GRANTS IN CHEMOPREVENTION NIH GUIDE, Volume 23, Number 26, July 15, RFA: CA P.T. 34 Keywords: Cancer/Carcinogenesis Chemoprevention Biomedical Research, Multidiscipl National Cancer Institute Letter of Intent Receipt Date: September 1, Application Receipt Date: October 20, PURPOSE The Division of . The latest cancer news from the U.S. government's principal agency for cancer research, plus resources designed for science writers and reporters. News & Events - National Cancer Institute Skip . The Chemopreventive Agent Development Research Group promotes and supports research on cancer preventive agent development, from preclinical studies to phase I clinical trials. The group’s projects aim to intercept the carcinogenic process by identifying and developing preventative agents with the potential to block, reverse, or delay the early stages of cancer.